Mary&May
Spicule Retinol PDRN Cream
A medium holy trinity active for acne and aging, built around Retinol and Retinoid, with reviewed formula data, and low obvious irritation flags.
Routine step
Serums & Treatments
Category
Holy Trinity Active
When to use
Night
Skin fit
Acne
10/10
Aging
10/10
Texture
10/10
Pores
6/10
Best for
Ingredient highlights
Niacinamide
Supports barrier function, oil balance, and more even tone
Panthenol
Helps soothe skin and reduce moisture loss
Retinol
Supports cell turnover and softens visible lines
Cautions
Best kept for night. Some actives do not play nicely with daytime sun.
Go slow if your skin is new to actives. Start a few nights a week.
Avoid during pregnancy or nursing unless your clinician says it is okay.
Acne-prone skin should patch-test first. A few ingredients may clog pores for some people.
Full ingredients
Formula source and INCI list
Koracle has a reviewed formula record for this product.
Koracle has a reviewed ingredient source for this product.
Aqua(Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12- 20 Alkyl Glucoside
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Koracle is skincare education, not medical or dermatology advice. Patch-test new products. Ask a licensed dermatologist about acne, rosacea, eczema, allergic reactions, pregnancy concerns, or symptoms that persist.